Endoxaban Level Determination

Calibrators and controls now available

Edoxaban (Lixiana®) is a direct Factor Xa-Inhibitor. Edoxaban inhibits, as Rivaroxaban and Apixaban, directly, selectively and reversibly both free and in prothrombinase complex bound Factor Xa. The advantages of this substance are found in the oral dispensing form and the well predictable pharmacokinetics and anticoagulation. According to the manufacturer dose regulation and routine monitoring is consequently unnecessary.


However, in case of compliance control respectively by overdoses a quantitative activity determination may be necessary. That requires a suitable routine and automated test application.


Now CE-marked calibration- and control plasmas are available that with COAMATIC® Heparin, a widely distributed and in praxis since many years reliable anti-Factor Xa-method makes the determination of Edoxaban possible.


Test package

Chromogenic method for anti-Factor Xa-determinationCOAMATIC® Heparin1 Kit41708

Calibration plasma Edoxaban

For calibration by determination of Edoxaban with chromogenic anti-Factor Xa-methods.


0 to ~500 ng/ml


Control plasma Edoxaban

For quality control by determination of Edoxaban with chromogenic anti-Factor Xa-methods.

Control plasmas

in 3 different concentrations (~ 30 ng/ml, ~  125 ng/ml und ∼ 400 ng/ml).






System of Haemostasis

The Flash file 
shows the system 
of haemostasis