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Rivaroxaban Level Determination
Calibrators and controls now available
Rivaroxaban (Xarelto®) is the first available direct Factor Xa-Inhibitor. It inhibits selectively and reversibly both free and in prothrombinase complex bound Factor Xa. The advantages of this substance are found in the oral dispensing form and the well predictable pharmacokinetics and anticoagulation. According to the manufacturer dose regulation and routine monitoring is consequently unnecessary.
However, in case of compliance control respectively by overdoses a quantitative activity determination may be necessary. That requires a suitable routine and automated test application.
Now CE-marked calibration- and control plasmas are available that with COAMATIC® Heparin, a widely distributed and in praxis since many years reliable anti-Factor Xa-method makes the determination of Rivaroxaban possible.
Test package
| Chromogenic method for anti-Factor Xa-determination | COAMATIC® Heparin | 1 Kit | 41708 |
Calibration plasma Rivaroxaban
| For calibration by determination of Rivaroxaban in low and high range with chromogenic anti-Factor Xa-methods. | CAL Set 0 to ~150 ng/ml | 5 x 1 ml | 5090170 |
| CAL High Set 0 to ~500 ng/ml | 5 x 1 ml | 5090171 |
Control plasma Rivaroxaban
| For quality control by determination of Rivaroxaban with chromogenic anti-Factor Xa-methods. | Control plasmas in 3 different concentrations (~50, 150 to 300 ng/ml). | low | 5 x 1 ml | 5090172 |
| medium | 5 x 1 ml | 5090173 | ||
| high | 5 x 1 ml | 5090174 |